Four nutrients in one prescription, delivered to your door.
- Self-administered at home
- Syringes and pads included
- Provider reviewed
MIC+B12
Four nutrients. One provider-guided prescription.
A compounded injectable combining methionine, inositol, choline and methylcobalamin (vitamin B12), prescribed following evaluation by a licensed provider.
Starting at Standard price $119First month price $109/month$96/month with quarterly plan
Your prescription, clearly explainedCompounded MIC+B12 Injectable
- Active ingredients
- Methionine, inositol, choline, methylcobalamin (vitamin B12)
- B12 strength
- 1 mg/mL
- Dosage form
- Compounded injectable
- Supply
- 10 mL monthly / 30 mL quarterly
- Administration
- As directed by your prescribing provider
- Storage
- Follow your prescription label and pharmacy instructions
- Prescription
- Required
- Dispensed by
- VialsRX, a licensed U.S. pharmacy
The formulation shown is subject to your prescription and pharmacy availability.
What’s included
- Provider review
- Prescription, if appropriate
- Compounded medication
- Shipping
- Syringes and alcohol pads
- Ongoing care messaging
- Provider review
- Medication and supplies
- Free discreet 2-day shipping right to your door
Prescription required. Subject to provider approval. Compounded medications are not FDA-approved.
What's actually in MIC+B12?
Four ingredients. Four distinct biological roles.
Methionine
An essential amino acid involved in protein synthesis and methylation pathways.
Inositol
A naturally occurring compound that is part of cell membranes and takes part in cellular signaling.
Choline
An essential nutrient involved in cell-membrane structure, acetylcholine synthesis and lipid transport.
Methylcobalamin (vitamin B12)
A form of vitamin B12. Vitamin B12 is required for normal red blood cell formation, neurological function and DNA synthesis.
MIC+B12 combines these ingredients in one compounded prescription.
How the ingredients fit into metabolism
Metabolism is a system, not a switch.
Each ingredient has a place in normal physiology. Methionine takes part in amino-acid and methylation pathways, inositol in cellular signaling, choline in phospholipids and lipid transport, and vitamin B12 in one-carbon metabolism and normal red-cell and neurological function.
MIC+B12 provides these compounds through a compounded injectable formulation.
The biology, illustrated
Good to know
The questions people ask most. Open any one for the details.
What does "lipotropic" actually mean?
You may have heard MIC+B12 described with that word. It generally refers to compounds associated with aspects of lipid metabolism, transport or processing. Methionine, inositol and choline are commonly grouped together as "MIC" in compounded wellness formulations.
The fact that nutrients take part in lipid metabolism does not establish that injecting a combination of them causes the body to burn stored fat, or produces clinically meaningful weight loss.
Let's talk about B12
Vitamin B12 is required for normal red blood cell formation, neurological function and DNA synthesis. A B12 deficiency can cause megaloblastic anemia and symptoms including fatigue and weakness.
Correcting a vitamin B12 deficiency is different from claiming that additional B12 will increase energy in someone who isn't deficient.
Why methylcobalamin? Vivo's current formulation uses methylcobalamin, one of the forms of vitamin B12. The body also uses other forms, such as cyanocobalamin, after converting them. Vivo doesn't claim that methylcobalamin is clinically superior to cyanocobalamin.
What about energy?
Vitamin B12 deficiency can cause fatigue and weakness, and correcting a deficiency can address symptoms attributable to that deficiency. That doesn't establish that compounded MIC+B12 will increase how energetic every person feels.
Energy has more than one input
- Sleep
- Nutrition
- Iron and B12 status
- Activity
- Metabolic health
- Medications
- Underlying health conditions
What about weight loss?
Methionine, inositol and choline take part in biological processes related to metabolism. That does not establish compounded MIC+B12 as a treatment that independently causes clinically meaningful weight loss.
Vivo does not represent MIC+B12 as a substitute for nutrition, physical activity or evidence-based obesity treatment when those treatments are clinically indicated.
Why is MIC+B12 associated with weight management, then? Because the individual ingredients have biological roles involving metabolism, and formulations containing them are commonly marketed within weight-management programs.
Already receiving another treatment?
Patients sometimes ask about MIC+B12 while receiving other prescription therapies, including medications used for weight management.
Whether treatments can or should be used together depends on your health history, current medications, nutritional status and treatment plan. Using MIC+B12 alongside a GLP-1 medication requires provider review. Don't add MIC+B12 to another prescription regimen on your own.
New to injections?
If prescribed, your shipment includes the supplies needed to administer your medication according to the instructions from your provider and pharmacy.
Always follow the administration instructions that accompany your prescription. Don't change your dose or frequency without talking to your provider.
- Prepare your dose
- Administer as directed
- Rotate injection sites as instructed
- Dispose of used sharps properly
The process
How to obtain MIC+B12
Step 1 of 3: Online intake and provider review
The process starts with an online medical intake. A licensed provider reviews the health history submitted and, if appropriate, issues a prescription. Review is asynchronous by default. Some states require a synchronous visit, and a video visit may also be required if clinically indicated.
Step 2 of 3: Compounded and shipped
The prescription is prepared by a licensed US compounding pharmacy for the individual patient and shipped discreetly in temperature-controlled packaging, with directions for use from the prescribing provider.
Step 3 of 3: Ongoing provider messaging
After delivery, patients can message the care team and a licensed provider through the patient portal. Continued refills require periodic provider reassessment.
Starting MIC+B12 with Vivo
- Your prescription
- Use it exactly as directed by your provider and the dispensing pharmacy.
- Your routine
- Follow the prescribed dose and schedule. Don't change either without talking to your provider.
- Your response
- Individual experiences vary. There's no set timeline for noticing a change in energy, weight or any other wellness outcome.
- Your care
- Contact your care team with questions, side effects or changes in your health.
Questions, answered directly
What does MIC stand for?
Methionine, inositol and choline. MIC+B12 adds vitamin B12.
What type of B12 does Vivo use?
Methylcobalamin, according to the current formulation. Your prescription label lists the exact ingredients.
What does vitamin B12 do?
Vitamin B12 is required for normal red blood cell formation, neurological function and DNA synthesis. A deficiency can cause megaloblastic anemia and symptoms including fatigue and weakness.
What's the difference between methylcobalamin and cyanocobalamin?
Both are forms of vitamin B12. Methylcobalamin is one of the forms the body uses directly; cyanocobalamin becomes active after the body converts it. Vivo doesn't claim that either form is clinically superior.
What does "lipotropic" mean?
The term generally refers to compounds associated with aspects of lipid metabolism, transport or processing, and methionine, inositol and choline are often grouped under it. It describes a biological association, not an effect on body fat.
Is MIC+B12 a fat-burning injection?
No. MIC+B12 should not be understood as a drug shown to burn body fat. Its ingredients take part in biological processes involving metabolism, but that is different from demonstrating clinically meaningful fat loss from the compounded formulation.
Does MIC+B12 cause weight loss?
It isn't a weight-loss drug. Its ingredients have roles in metabolism, but that does not establish that compounded MIC+B12 causes clinically meaningful weight loss. It is not a substitute for nutrition, physical activity or evidence-based obesity treatment.
Will MIC+B12 increase my energy?
If you have a vitamin B12 deficiency, correcting it can address the fatigue and weakness that deficiency causes. That is different from adding B12 when you aren't deficient, and it doesn't establish that compounded MIC+B12 will increase how energetic you feel.
Can MIC+B12 help with fatigue?
Fatigue has many possible causes, including sleep, nutrition, iron or B12 status, medications and underlying health conditions. Your provider should consider those causes rather than assume B12 is the answer.
Does MIC+B12 detox the liver?
Vivo doesn't claim it does. Choline takes part in lipid transport, a process in which the liver is central. That is nutrient biology. It does not establish that compounded MIC+B12 "detoxes" or otherwise changes the liver.
Can I use MIC+B12 with a GLP-1?
That requires individual evaluation by your provider, based on your health history, current medications, nutritional status and treatment plan. Don't add MIC+B12 to another prescription regimen without provider review.
Is MIC+B12 the same as a B12 shot?
No. MIC+B12 contains methionine, inositol and choline in addition to vitamin B12.
How is MIC+B12 injected?
Exactly as the instructions that accompany your prescription direct. Your provider and the dispensing pharmacy give you prescription-specific instructions.
How often do I take it?
As prescribed. Don't change your dose or frequency without talking to your provider.
Does it need refrigeration?
Follow the storage instructions on your pharmacy label exactly.
Is compounded MIC+B12 FDA-approved?
No. Compounded medications are not FDA-approved, and FDA does not review them for safety, effectiveness or quality before they are marketed.
Is a prescription required?
Yes. MIC+B12 is available by prescription only. Every order starts with an online medical intake and review by a licensed provider, who determines whether a prescription is clinically appropriate. Patients must be 18 or older and physically located in a state where services are available, both at intake and at each refill. Services are currently available in all 50 US states, subject to state regulation.
What happens if a provider does not prescribe?
A card may be authorized at checkout and is charged only after a provider approves a prescription. If a licensed provider determines the medication is not clinically appropriate, no prescription is issued, no medication ships, and no charge is completed for that medication order.
Is a video visit required?
Provider review is asynchronous by default, based on the written intake. Some states require a synchronous visit (live video or phone) before a provider can prescribe, and a provider may also request one if clinically indicated.
Who prescribes, and who prepares the medication?
Prescriptions are issued by licensed providers. Medical leadership includes Dr. Sean Arora, M.D., and Dr. Shannon Arora, M.D. Prescriptions are prepared and shipped by a licensed US 503A compounding pharmacy. Vivo Health LLC operates the platform and does not practice medicine or dispense medication.
Is MIC+B12 FDA-approved?
No. MIC+B12 is a compounded medication prepared by a licensed pharmacy for an individual prescription. Compounded medications are not FDA-approved drug products.
Understand what's in your treatment.
Explore MIC+B12 through a provider-guided process.
Starting at Standard price $119First month price $109/month$96/month with quarterly plan
- Provider review
- Prescription required
- U.S. pharmacy fulfillment
Important information about compounded medications
Vivo is a telehealth platform and does not manufacture or compound medications. Treatment requires evaluation by a licensed healthcare provider. A prescription is issued only when the provider determines treatment is medically appropriate.
Compounded medications are not FDA-approved. FDA does not review compounded medications for safety, effectiveness or quality before they are marketed. Compounded medications may be prescribed when a healthcare provider determines that a compounded preparation is appropriate for an individual patient.
Information on this page is educational and does not replace individualized medical advice. Treatment availability, formulation and fulfillment may vary based on provider judgment and pharmacy availability.