Educational guide · Format & process
NAD+ nasal spray vs NAD+ face cream: how the two formats compare
Published
Vivo offers compounded NAD+ as a nasal spray used in the nose and as a face cream applied to the skin. Both require an online intake and licensed provider review, and your provider decides which form, if any, is appropriate. Compounded medications are not FDA-approved.
This guide compares the two formats on practical points only: what each one is, how it’s used, what comes in each order, and what it costs. It isn’t dosing advice, and it doesn’t compare how well either format works.
| NAD+ Nasal Spray | NAD+ Face Cream | |
|---|---|---|
| Form | Compounded nasal spray in a bottle | Compounded topical cream |
| Route | Intranasal (in the nose) | Topical (applied to the skin) |
| Needles | None | None |
| Strengths and sizes listed on Vivo | 300 mg/mL × 15 mL, 300 mg/mL × 30 mL, 150 mg/mL × 15 mL | As prescribed by your provider |
| Directions | As prescribed by your provider | As prescribed by your provider |
| Storage | Follow your prescription label and pharmacy instructions | Follow your prescription label and pharmacy instructions |
| Prepared by | VialsRX, a state-licensed U.S. 503A compounding pharmacy | VialsRX, a state-licensed U.S. 503A compounding pharmacy |
| Shipping | Free discreet 2-day shipping | Free discreet 2-day shipping |
| Product page | NAD+ Nasal Spray | NAD+ Face Cream |
This table compares format and logistics only. It doesn’t compare effectiveness, and your provider decides which form, if any, is appropriate for you.
How each format is used
Nasal spray. You use it at home, in the nose, following the directions on your prescription label.
Face cream. You apply it to the skin at home, following the directions on your prescription label.
For either format, follow the storage instructions on your label. If you have questions about how to use your prescription, message your care team.
Practical factors a provider may consider
Which format, if either, makes sense is a decision for your provider after reviewing your intake. Practical points that often come up in that conversation include:
- Where it’s used. The nasal spray is used in the nose. The cream is applied to the skin.
- Routine and handling. Each product comes with its own label and pharmacy instructions.
- Supply. The nasal spray is offered in more than one strength and bottle size. Your provider determines which, if any, is prescribed.
- Price. Monthly prices differ by format. See the table below.
This is not a ranking. Neither format is presented here as better than the other.
How prescribing works at Vivo
- Online intake. You complete a health-history form online at vivoclinic.org/start.
- Provider review. A licensed provider reviews your intake. Review is asynchronous by default. Some states require a synchronous visit, and a video visit may be required if clinically indicated.
- Prescription, if appropriate. Your provider decides whether a prescription for NAD+, and in which form, is appropriate for you. If it isn’t, no prescription is issued, and you are not charged for medication. Entering payment information at checkout authorizes your payment method — it does not capture a charge. A charge is captured only after a provider approves the prescription.
- Licensed compounding pharmacy. If prescribed, your medication is prepared and dispensed by VialsRX, a state-licensed U.S. 503A compounding pharmacy, with directions for use written by your provider.
- Shipping and ongoing care. Your prescription ships free with discreet 2-day shipping. You can message your care team after delivery. There’s no minimum term, and you can cancel anytime from your dashboard or by emailing care@vivoclinic.org.
| Product | First month | Then | Quarterly plan |
|---|---|---|---|
| NAD+ Nasal Spray, 300 mg/mL × 15 mL | $119 | $129/month | — |
| NAD+ Nasal Spray, 300 mg/mL × 30 mL | $139 | $209/month | — |
| NAD+ Nasal Spray, 150 mg/mL × 15 mL | $135 | $159/month | $120/month with quarterly plan |
| NAD+ Face Cream | $119 | $129/month | $83/month with quarterly plan |
Pricing may change, so check /nad, /nad-cream, and your checkout disclosure for the current price.
Checkout accepts HSA and FSA cards. Accepting a card doesn’t mean your plan will treat the purchase as an eligible expense. Your plan administrator decides that.
Frequently asked questions
What’s the difference between NAD+ nasal spray and NAD+ face cream?
They’re two formats of compounded NAD+. The nasal spray is used in the nose. The face cream is applied to the skin. Both are prescription-only, prepared by a licensed compounding pharmacy, and used as prescribed by your provider.
Which is better, NAD+ nasal spray or NAD+ cream?
Vivo doesn’t rank one format over the other. Your provider reviews your intake and decides which form, if any, is appropriate.
Do both formats need a prescription?
Yes. At Vivo, both NAD+ Nasal Spray and NAD+ Face Cream are compounded prescription medications. A licensed provider must review your intake and approve a prescription before the pharmacy can prepare and dispense either one.
Are compounded NAD+ nasal spray and cream FDA-approved?
No. Compounded medications are prepared by licensed pharmacies for individual prescriptions and are not FDA-approved drug products. FDA does not review them for safety, effectiveness, or manufacturing quality before they are dispensed.
How much do NAD+ nasal spray and NAD+ face cream cost at Vivo?
As of October 17, 2026, NAD+ Nasal Spray 300 mg/mL × 15 mL is $119 for the first month, then $129/month. NAD+ Face Cream is $119 for the first month, then $129/month, or $83/month with quarterly plan. There’s no minimum term, and you can cancel anytime.
What happens if I’m not approved?
No prescription is issued, and you are not charged for medication. Entering payment information at checkout authorizes your payment method — it does not capture a charge. A charge is captured only after a provider approves the prescription.
Can I use an HSA or FSA card?
Vivo’s checkout accepts HSA and FSA cards. Whether a purchase counts as an eligible expense is decided by your plan administrator, not by Vivo.
Prescription required. Subject to provider approval. Compounded medications are not FDA-approved. This guide is educational and isn’t medical advice.
Sources
- Compounding and the FDA: Questions and Answers — U.S. Food and Drug Administration
- Terms of Service — Vivo Health LLC